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Avian Antibody Platform
The Structural Biotechnology laboratory is coordinating a technological platform for the production of antibodies in avian models. The lab is engaged in the development of an avian facility working under Directive 2010/63/EU on the protection of animals used for scientific purposes.
The activities of the platform take advantage of a unique animal model for antibody production, combined with the lab expertise in expression and purification of recombinant protein antigens.
The Structural Biotechnology laboratory welcomes collaborative proposals for the development of antibodies for research, diagnostics and therapeutic applications.

Technological Platform for the development of Egg-based Biopharmaceuticals
We have been combining the use of avian model hosts for antibody generation with structural and functional rationalization of potential microbial therapeutic targets and vaccine antigens. We implemented an avian antibody platform for the development of target-specific immunological libraries in Coturnix japonica model hosts.

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Collaborations

Mara G. Freire
CICECO – Aveiro Institute of Materials, Dep. Chemistry, University of Aveiro (Aveiro, Portugal)

Isaura Simões
LSU School of Veterinary Medicine, Dep. Pathobiological Sciences (Baton Rouge, LA, USA)
CNC – Center for Neuroscience and Cell Biology, University of Coimbra (Coimbra, Portugal)

Isabel Fidalgo-Carvalho
Equigerminal S.A., Biocant (Cantanhede, Portugal)

João Morais-Cabral
IBMC – Institute for Molecular and Cell Biology, University of Porto (Porto, Portugal)

Paula Gameiro
REQUIMTE- Dep. Chemistry and Biochemistry, Faculty of Sciences, University of Porto (Porto, Portugal)

Bruno Correia
Ecole Polytechnique Fédérale de Lausanne – EPFL (Lausanne, Switzerland)

Ana Catarina Gomes
Biocant (Cantanhede, Portugal)

Miguel Viveiros
IHMT – Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon (Lisbon, Portugal)

Nuno Santos
IBMC – Institute for Molecular and Cell Biology, University of Porto (Porto, Portugal)

Miguel Mano
CNC – Center for Neuroscience and Cell Biology, University of Coimbra (Coimbra, Portugal)

Ana Eulálio
CNC – Center for Neuroscience and Cell Biology, University of Coimbra (Coimbra, Portugal)

Kirill Alexandrov
IMB – Institute for Molecular Bioscience, University of Queensland (Queensland, Australia)